According to filmmaker Susanna Styron’s Out of My Head, migraine attacks afflict nearly one billion people, 75 percent of them women, including Styron’s daughter Emma. In an effort to help Emma, Styron began researching the condition and here she interweaves her findings with a running account (often in animated clips by Maya Edelman) of her daughter’s progress with various treatments. Although Styron’s initial characterization of migraines as a 'hidden' disease seems overstated (who doesn’t know someone who has migraines?), her exploration reveals many aspects that will be unfamiliar to most viewers (such as the phenomenon of 'abdominal migraines') while also laying to rest some common misconceptions (migraines are not just bad headaches). Along the way, Styron interviews numerous physicians (one notes that the U.S. has a mere 500 headache specialists), who talk about the scandalous lack of funding for migraine research, discuss the many symptoms associated with migraine (including aphasia, dramatically illustrated here with a clip of reporter Serene Branson becoming incoherent while on camera outside the 2011 Grammy Awards), and various treatments available (ranging from the triptan family of drugs to holistic medicine approaches). Styron also interviews a number of migraine sufferers, including author Siri Hustvedt (with a companion’s perspective presented by her novelist husband Paul Auster) and Joan Didion, who reads from her classic essay on migraine, 'In Bed.' Styron, who incidentally is the daughter of late novelist William Styron, also notes many historical figures who either had (or likely had) migraines, such as Hildegard of Bingen (whose religious visions closely match descriptions of migraine experiences), Lewis Carroll, Sigmund Freud, Georgia O’Keefe, Virginia Woolf, and Thomas Jefferson. Featuring both the full-length version and a 57-minute educational edition, extras include bonus scenes and audio description. Sure to be of interest to those who endure migraine attacks (or have family members or friends who suffer), this is recommended. Aud: C, P. (R. Pitman)